Structural Basis for Substrate Specificity in Human Monomeric Carbonyl Reductases

Carbonyl reduction constitutes a phase I reaction for many xenobiotics and is carried out in mammals mainly by members of two protein families, namely aldo-keto reductases and short-chain dehydrogenases/reductases. In addition to their capacity to reduce xenobiotics, several of the enzymes act on en...

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Bibliografiske detaljer
Main Authors: Pilka, Ewa S., Niesen, Frank H., Lee, Wen Hwa, El-Hawari, Yasser, Dunford, James E., Kochan, Grazyna, Wsol, Vladimir, Martin, Hans-Joerg, Maser, Edmund, Oppermann, Udo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741203/
https://ncbi.nlm.nih.gov/pubmed/19841672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007113
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