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Structural Basis for Substrate Specificity in Human Monomeric Carbonyl Reductases
Carbonyl reduction constitutes a phase I reaction for many xenobiotics and is carried out in mammals mainly by members of two protein families, namely aldo-keto reductases and short-chain dehydrogenases/reductases. In addition to their capacity to reduce xenobiotics, several of the enzymes act on en...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741203/ https://ncbi.nlm.nih.gov/pubmed/19841672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007113 |
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