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RSV-induced dysregulation of expression of a mucosal β-defensin augments colonization of the upper airway by nontypeable Haemophilus influenzae

Otitis media (OM) is a polymicrobial disease wherein upper respiratory tract (URT) viruses compromise host airway defenses, which allows bacterial flora of the nasopharynx (NP) access to the middle ear. We have shown, in vitro, that respiratory syncytial virus (RSV), a viral co-pathogen of OM, reduc...

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Bibliografiske detaljer
Main Authors: McGillivary, Glen, Mason, Kevin M., Jurcisek, Joseph A., Peeples, Mark E., Bakaletz, Lauren O.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741182/
https://ncbi.nlm.nih.gov/pubmed/19500108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2009.01339.x
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