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RSV-induced dysregulation of expression of a mucosal β-defensin augments colonization of the upper airway by nontypeable Haemophilus influenzae

Otitis media (OM) is a polymicrobial disease wherein upper respiratory tract (URT) viruses compromise host airway defenses, which allows bacterial flora of the nasopharynx (NP) access to the middle ear. We have shown, in vitro, that respiratory syncytial virus (RSV), a viral co-pathogen of OM, reduc...

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Autori principali: McGillivary, Glen, Mason, Kevin M., Jurcisek, Joseph A., Peeples, Mark E., Bakaletz, Lauren O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741182/
https://ncbi.nlm.nih.gov/pubmed/19500108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2009.01339.x
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