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Inteferons pen the JAK-STAT pathway
Characterization of how IFNs mediate their biological response led to identification of the JAK-STAT signaling cascade, where JAKs are receptor-associated kinases and STATs the transcription factors they activate. Today, 4 JAKs and 7 STATs are known to transduce pivotal signals for the over 50 membe...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741134/ https://ncbi.nlm.nih.gov/pubmed/18765289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2008.08.010 |
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