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Elevated protein kinase C alpha expression may be predictive of tamoxifen treatment failure

We previously reported that stable transfection of protein kinase C alpha (PKCα) into T47D human breast cancer cells results in tamoxifen (TAM)-resistant tumour growth. Relevance of PKCα expression in clinical specimens was determined by comparing PKCα expression in tumours from patients exhibiting...

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Détails bibliographiques
Auteurs principaux: Tonetti, D A, Morrow, M, Kidwai, N, Gupta, A, Badve, S
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741052/
https://ncbi.nlm.nih.gov/pubmed/12778068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600923
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