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Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function

Oestrogen receptor alpha (ERα) is an oestrogen-activated transcription factor, which regulates proliferation and differentiation of mammary epithelial cells by activating or repressing gene expression. ERα is a critical prognostic indicator and a therapeutic target for breast cancer. Patients with t...

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Detalhes bibliográficos
Main Authors: Bhat-Nakshatri, P, Campbell, R A, Patel, N M, Newton, T R, King, A J, Marshall, M S, Ali, S, Nakshatri, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410160/
https://ncbi.nlm.nih.gov/pubmed/14970864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601541
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