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Absence of BRAF gene mutations in uveal melanomas in contrast to cutaneous melanomas

The recent discovery of activating mutations in the BRAF gene in many cutaneous melanomas led us to screen the genomic sequence of BRAF exons 11 and 15 in a series of 48 intraocular (uveal) melanomas, together with control samples from three cutaneous melanomas and the SK-Mel-28 cell line, which has...

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Main Authors: Edmunds, S C, Cree, I A, Dí Nícolantonío, F, Hungerford, J L, Hurren, J S, Kelsell, D P
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741050/
https://ncbi.nlm.nih.gov/pubmed/12778069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600919
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