Mechanisms of local immunosuppression in cutaneous melanoma

Cutaneous melanoma is highly immunogenic, yet primary melanomas and metastases develop successfully in otherwise immunocompetent patients. To investigate the local immunosuppressive microenvironment, we examined the presence of suppressor T lymphocytes and tolerising dendritic cells (DCs), the expre...

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Bibliografiske detaljer
Main Authors: Polak, M E, Borthwick, N J, Gabriel, F G, Johnson, P, Higgins, B, Hurren, J, McCormick, D, Jager, M J, Cree, I A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359967/
https://ncbi.nlm.nih.gov/pubmed/17565341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603763
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