Mechanisms of local immunosuppression in cutaneous melanoma

Cutaneous melanoma is highly immunogenic, yet primary melanomas and metastases develop successfully in otherwise immunocompetent patients. To investigate the local immunosuppressive microenvironment, we examined the presence of suppressor T lymphocytes and tolerising dendritic cells (DCs), the expre...

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Detalhes bibliográficos
Main Authors: Polak, M E, Borthwick, N J, Gabriel, F G, Johnson, P, Higgins, B, Hurren, J, McCormick, D, Jager, M J, Cree, I A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359967/
https://ncbi.nlm.nih.gov/pubmed/17565341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603763
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