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Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro
Cell adhesion to extracellular matrix (ECM) is thought to confer resistance against cell-damaging agents, that is, drugs and radiation, in tumour and normal cells in vitro. The dependence of cell survival on β1-integrin-linked kinase (ILK), protein kinase Bα/Akt (PKBα/Akt) and glycogen synthase kina...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2003
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741045/ https://ncbi.nlm.nih.gov/pubmed/12778079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600912 |
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