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Crystal Structure of a Trypanocidal 4,4′-Bis(imidazolinylamino)diphenylamine Bound to DNA
The pursuit of small molecules that bind to DNA has led to the discovery of selective and potent antitrypanosomal agents, specifically 4,4′-bis(imidazolinylamino) and 4,4′-bis(guanidino) diphenylamine compounds, CD27 and CD25, respectively. Although the antitrypanosomal properties of these compounds...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740933/ https://ncbi.nlm.nih.gov/pubmed/19405506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900204w |
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