Guidelines for the clinical management of Lynch syndrome (hereditary non‐polyposis cancer)

Lynch syndrome (hereditary non‐polyposis colorectal cancer) is characterised by the development of colorectal cancer, endometrial cancer and various other cancers, and is caused by a mutation in one of the mismatch repair genes: MLH1, MSH2, MSH6 or PMS2. The discovery of these genes, 15 years ago, h...

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Main Authors: Vasen, H F A, Möslein, G, Alonso, A, Bernstein, I, Bertario, L, Blanco, I, Burn, J, Capella, G, Engel, C, Frayling, I, Friedl, W, Hes, F J, Hodgson, S, Mecklin, J‐P, Møller, P, Nagengast, F, Parc, Y, Renkonen‐Sinisalo, L, Sampson, J R, Stormorken, A, Wijnen, J
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2007
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740877/
https://ncbi.nlm.nih.gov/pubmed/17327285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2007.048991
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