Guidelines for the clinical management of Lynch syndrome (hereditary non‐polyposis cancer)

Lynch syndrome (hereditary non‐polyposis colorectal cancer) is characterised by the development of colorectal cancer, endometrial cancer and various other cancers, and is caused by a mutation in one of the mismatch repair genes: MLH1, MSH2, MSH6 or PMS2. The discovery of these genes, 15 years ago, h...

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Detalhes bibliográficos
Main Authors: Vasen, H F A, Möslein, G, Alonso, A, Bernstein, I, Bertario, L, Blanco, I, Burn, J, Capella, G, Engel, C, Frayling, I, Friedl, W, Hes, F J, Hodgson, S, Mecklin, J‐P, Møller, P, Nagengast, F, Parc, Y, Renkonen‐Sinisalo, L, Sampson, J R, Stormorken, A, Wijnen, J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740877/
https://ncbi.nlm.nih.gov/pubmed/17327285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2007.048991
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