THE EPENDYMAL ROUTE FOR INSULIN-LIKE GROWTH FACTOR-1 GENE THERAPY IN THE BRAIN

Intracerebroventricular administration of the peptide insulin-like growth factor-1 (IGF-1) has been shown to be an effective neuroprotective strategy in the brain of different animal models, a major advantage being the achievement of high concentrations of IGF-1 in the brain without altering serum l...

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Main Authors: Hereñú, Claudia B., Sonntag, William E., Morel, Gustavo R., Portiansky, Enrique L., Goya, Rodolfo G.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740751/
https://ncbi.nlm.nih.gov/pubmed/19531373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.06.024
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