Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke

Pathological conditions in the central nervous system, including stroke and trauma, are often exacerbated by cerebral edema. We recently identified a nonselective cation channel, the NC(Ca-ATP) channel, in ischemic astrocytes that is regulated by sulfonylurea receptor 1 (SUR1), is opened by depletio...

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Huvudupphovsmän: Simard, J Marc, Chen, Mingkui, Tarasov, Kirill V, Bhatta, Sergei, Ivanova, Svetlana, Melnitchenko, Ludmila, Tsymbalyuk, Natalya, West, G Alexander, Gerzanich, Volodymyr
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740734/
https://ncbi.nlm.nih.gov/pubmed/16550187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1390
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