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Intracellular metabolism of favipiravir (T-705) in uninfected and influenza A (H5N1) virus-infected cells
OBJECTIVES: To determine the metabolism of favipiravir (T-705, 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) to its ribosylated, triphosphorylated form (T-705 RTP) in uninfected and influenza A/Duck/MN/1525/81 (H5N1) virus-infected cells. Effects of treatment on intracellular guanosine triphosphate (GTP...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740635/ https://ncbi.nlm.nih.gov/pubmed/19643775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp274 |
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