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YcbX and yiiM, two novel determinants for resistance of E. coli to N-hydroxylated base analogs

We have shown previously that lack of molybdenum cofactor (MoCo) in Escherichia coli leads to hypersensitivity to the mutagenic and toxic effects of N-hydroxylated base analogs, such as 6-N-hydroxylaminopurine (HAP). However, the nature of the MoCo-dependent mechanism is unknown, as inactivation of...

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Detalhes bibliográficos
Main Authors: Kozmin, Stanislav G., Leroy, Prune, Pavlov, Youri I., Schaaper, Roel M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740630/
https://ncbi.nlm.nih.gov/pubmed/18312271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06128.x
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