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TusA (YhhP) and IscS are required for molybdenum cofactor-dependent base-analog detoxification
Lack of molybdenum cofactor (Moco) in Escherichia coli leads to hypersensitivity to the mutagenic and toxic effects of N-hydroxylated base analogs, such as 6-N-hydroxylaminopurine (HAP). This phenotype is due to the loss of two Moco-dependent activities, YcbX and YiiM, that are capable of reducing H...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831636/ https://ncbi.nlm.nih.gov/pubmed/23894086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.108 |
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