A Role for HSP70 in Protecting against Indomethacin-induced Gastric Lesions

A major clinical problem encountered with the use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as indomethacin, is gastrointestinal complications. Both NSAID-dependent cyclooxygenase inhibition and gastric mucosal apoptosis are involved in NSAID-produced gastric lesions, and this apoptosis...

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Détails bibliographiques
Auteurs principaux: Suemasu, Shintaro, Tanaka, Ken-Ichiro, Namba, Takushi, Ishihara, Tomoaki, Katsu, Takashi, Fujimoto, Mitsuaki, Adachi, Hiroaki, Sobue, Gen, Takeuchi, Koji, Nakai, Akira, Mizushima, Tohru
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Mechanisms of Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740595/
https://ncbi.nlm.nih.gov/pubmed/19439408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006817
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