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Crystal Structure of Iodotyrosine Deiodinase, a Novel Flavoprotein Responsible for Iodide Salvage in Thyroid Glands

The flavoprotein iodotyrosine deiodinase (IYD) salvages iodide from mono- and diiodotyrosine formed during the biosynthesis of the thyroid hormone thyroxine. Expression of a soluble domain of this membrane-bound enzyme provided sufficient material for crystallization and characterization by x-ray di...

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Main Authors: Thomas, Seth R., McTamney, Patrick M., Adler, Jennifer M., LaRonde-LeBlanc, Nicole, Rokita, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740591/
https://ncbi.nlm.nih.gov/pubmed/19436071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013458
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