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Rapid Kinetics of Dehalogenation Promoted by Iodotyrosine Deiodinase from Human Thyroid

[Image: see text] Reductive dehalogenation such as that catalyzed by iodotyrosine deiodinase (IYD) is highly unusual in aerobic organisms but necessary for iodide salvage from iodotyrosine generated during thyroxine biosynthesis. Equally unusual is the dependence of this process on flavin. Rapid kin...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Bobyk, Kostyantyn D., Ballou, David P., Rokita, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938124/
https://ncbi.nlm.nih.gov/pubmed/26151430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00410
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