The p160 Coactivator PAS-B Motif Stabilizes Nuclear Receptor Binding and Contributes to Isoform-specific Regulation by Thyroid Hormone Receptors

Thyroid hormone receptors (TRs) are hormone-regulated transcription factors that play multiple roles in vertebrate endocrinology and development. TRs are expressed as a series of distinct receptor isoforms that mediate different biological functions. The TRβ2 isoform is expressed primarily in the hy...

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Autors principals: Privalsky, Martin L., Lee, Sangho, Hahm, Johnnie B., Young, Briana M., Fong, Rebecca N. G., Chan, Ivan H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Transcription, Chromatin, and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740581/
https://ncbi.nlm.nih.gov/pubmed/19487700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007542
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