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Proinsulin and the Genetics of Diabetes Mellitus
Insulin plays a central role in the regulation of vertebrate metabolism. The hormone, the post-translational product of a single-chain precursor, is a globular protein containing two chains, A (21 residues) and B (30 residues). Recent advances in human genetics have identified dominant mutations in...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740536/ https://ncbi.nlm.nih.gov/pubmed/19395706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.009936 |
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