The N Terminus of Connexin37 Contains an α-Helix That Is Required for Channel Function

The cytoplasmic N-terminal domain of connexins has been implicated in multiple aspects of gap junction function, including connexin trafficking/assembly and channel gating. A synthetic peptide corresponding to the first 23 amino acids of human connexin37 was prepared, and circular dichroism and nucl...

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Bibliografiske detaljer
Main Authors: Kyle, John W., Berthoud, Viviana M., Kurutz, Josh, Minogue, Peter J., Greenspan, Michael, Hanck, Dorothy A., Beyer, Eric C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Membrane Transport, Structure, Function, and Biogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740466/
https://ncbi.nlm.nih.gov/pubmed/19478091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016907
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