Yüklüyor......

Insulin-like Growth Factor-I Prevents the Accumulation of Autophagic Vesicles and Cell Death in Purkinje Neurons by Increasing the Rate of Autophagosome-to-lysosome Fusion and Degradation

Continuous macroautophagic activity is critical for the maintenance of neuronal homeostasis; however, unchecked or dysregulated autophagy can lead to cell death. Cultured Purkinje neurons die by an autophagy-associated cell death mechanism when deprived of trophic support. Here, we report that insul...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Bains, Mona, Florez-McClure, Maria L., Heidenreich, Kim A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740464/
https://ncbi.nlm.nih.gov/pubmed/19509289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011791
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!