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E(2)P State Stabilization by the N-terminal Tail of the H,K-ATPase β-Subunit Is Critical for Efficient Proton Pumping under in Vivo Conditions

The catalytic α-subunits of Na,K- and H,K-ATPase require an accessory β-subunit for proper folding, maturation, and plasma membrane delivery but also for cation transport. To investigate the functional significance of the β-N terminus of the gastric H,K-ATPase in vivo, several N-terminally truncated...

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Detalhes bibliográficos
Main Authors: Dürr, Katharina L., Abe, Kazuhiro, Tavraz, Neslihan N., Friedrich, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740441/
https://ncbi.nlm.nih.gov/pubmed/19491099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.005769
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