C Terminus of Hsc70-interacting Protein Promotes Smooth Muscle Cell Proliferation and Survival through Ubiquitin-mediated Degradation of FoxO1

Forkhead transcription factors (FoxOs) play a pivotal role in controlling cellular proliferation and survival. The cellular level of these factors is tightly regulated through the phosphoinositide 3-kinase/Akt and ubiquitin-mediated degradation. However, the ubiquitin ligases responsible for the deg...

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Bibliographic Details
Main Authors: Li, Fang, Xie, Ping, Fan, Yongna, Zhang, Hua, Zheng, Lianfang, Gu, Dongfeng, Patterson, Cam, Li, Huihua
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740435/
https://ncbi.nlm.nih.gov/pubmed/19483080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017046
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