Liver-specific Deletion of the Growth Hormone Receptor Reveals Essential Role of Growth Hormone Signaling in Hepatic Lipid Metabolism

Growth hormone (GH) plays a pivotal role in growth and metabolism, with growth promotion mostly attributed to generation of insulin-like growth factor I (IGF-I) in liver or at local sites of GH action, whereas the metabolic effects of GH are considered to be intrinsic to GH itself. To distinguish th...

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Hlavní autoři: Fan, Yong, Menon, Ram K., Cohen, Pinchas, Hwang, David, Clemens, Thomas, DiGirolamo, Douglas J., Kopchick, John J., Le Roith, Derek, Trucco, Massimo, Sperling, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Metabolism and Bioenergetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740419/
https://ncbi.nlm.nih.gov/pubmed/19460757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014308
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