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Suppression of Rft1 Expression Does Not Impair the Transbilayer Movement of Man(5)GlcNAc(2)-P-P-Dolichol in Sealed Microsomes from Yeast

To further evaluate the role of Rft1 in the transbilayer movement of Man(5)GlcNAc(2)-P-P-dolichol (M5-DLO), a series of experiments was conducted with intact cells and sealed microsomal vesicles. First, an unexpectedly large accumulation (37-fold) of M5-DLO was observed in Rft1-depleted cells (YG113...

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Autori principali: Rush, Jeffrey S., Gao, Ningguo, Lehrman, Mark A., Matveev, Sergey, Waechter, Charles J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740409/
https://ncbi.nlm.nih.gov/pubmed/19494107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.000893
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