Scavenger Receptor BI Protects against Septic Death through Its Role in Modulating Inflammatory Response

Sepsis is a leading cause of death that is characterized by uncontrolled inflammatory response. In this study, we report that scavenger receptor BI (SR-BI), a high density lipoprotein receptor, is a critical survival factor of sepsis. We induced sepsis using an established septic animal model, cecal...

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Bibliographic Details
Main Authors: Guo, Ling, Song, Zhiqing, Li, Mengting, Wu, Qingan, Wang, Dan, Feng, Hong, Bernard, Philip, Daugherty, Alan, Huang, Bin, Li, Xiang-An
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740408/
https://ncbi.nlm.nih.gov/pubmed/19491399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.020933
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