Modulation of the Membrane Type 1 Matrix Metalloproteinase Cytoplasmic Tail Enhances Tumor Cell Invasion and Proliferation in Three-dimensional Collagen Matrices

Increasing evidence suggests that the cytoplasmic tail of membrane type 1 matrix metalloproteinase (MT1-MMP) is subject to phos pho ryl a tion and that this modification may influence its enzymatic activity at the cell surface. In this study, phos pho ryl a ted MT1-MMP is detected using a phospho-sp...

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Main Authors: Moss, Natalie M., Wu, Yi I., Liu, Yueying, Munshi, H. G., Stack, M. Sharon
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Enzyme Catalysis and Regulation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740404/
https://ncbi.nlm.nih.gov/pubmed/19458085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.020362
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