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Increased Hox activity mimics the teratogenic effects of excess retinoic acid signaling
Excess retinoic acid (RA) signaling can be teratogenic and result in cardiac birth defects, but the cellular and molecular origins of these defects are not well understood. Excessive RA signaling can completely eliminate heart formation in the zebrafish embryo. However, atrial and ventricular cells...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739864/ https://ncbi.nlm.nih.gov/pubmed/19384962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21951 |
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