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Resolving deconvolution ambiguity in gene alternative splicing

BACKGROUND: For many gene structures it is impossible to resolve intensity data uniquely to establish abundances of splice variants. This was empirically noted by Wang et al. in which it was called a "degeneracy problem". The ambiguity results from an ill-posed problem where additional inf...

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Autors principals: She, Yiyuan, Hubbell, Earl, Wang, Hui
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739860/
https://ncbi.nlm.nih.gov/pubmed/19653895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-237
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