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Resolving deconvolution ambiguity in gene alternative splicing

BACKGROUND: For many gene structures it is impossible to resolve intensity data uniquely to establish abundances of splice variants. This was empirically noted by Wang et al. in which it was called a "degeneracy problem". The ambiguity results from an ill-posed problem where additional inf...

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Detalhes bibliográficos
Main Authors: She, Yiyuan, Hubbell, Earl, Wang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739860/
https://ncbi.nlm.nih.gov/pubmed/19653895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-237
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