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Resolving deconvolution ambiguity in gene alternative splicing

BACKGROUND: For many gene structures it is impossible to resolve intensity data uniquely to establish abundances of splice variants. This was empirically noted by Wang et al. in which it was called a "degeneracy problem". The ambiguity results from an ill-posed problem where additional inf...

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Autori principali: She, Yiyuan, Hubbell, Earl, Wang, Hui
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739860/
https://ncbi.nlm.nih.gov/pubmed/19653895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-237
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