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Resolving deconvolution ambiguity in gene alternative splicing

BACKGROUND: For many gene structures it is impossible to resolve intensity data uniquely to establish abundances of splice variants. This was empirically noted by Wang et al. in which it was called a "degeneracy problem". The ambiguity results from an ill-posed problem where additional inf...

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Hlavní autoři: She, Yiyuan, Hubbell, Earl, Wang, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739860/
https://ncbi.nlm.nih.gov/pubmed/19653895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-237
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