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The JNK MAP kinase pathway contributes to the development of endotoxin-induced diaphragm caspase activation

We previously demonstrated that endotoxin-induced sepsis results in caspase 8-mediated diaphragmatic dysfunction. The upstream signaling pathways modulating diaphragm caspase 8 activation in response to endotoxin administration are, however, unknown. The purpose of the present study was to test the...

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Autori principali: Supinski, Gerald S., Ji, Xinying, Callahan, Leigh Ann
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739795/
https://ncbi.nlm.nih.gov/pubmed/19605759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90849.2008
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