Highly sensitive quantification of serum malonate, a possible marker for de novo lipogenesis, by LC-ESI-MS/MS

We describe a new sensitive and specific method for the quantification of serum malonate (malonic acid, MA), which could be a new biomarker for de novo lipogenesis (fatty acid synthesis). This method is based upon a stable isotope-dilution technique using LC-MS/MS. MA from 50 μl of serum was derivat...

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Main Authors: Honda, Akira, Yamashita, Kouwa, Ikegami, Tadashi, Hara, Takashi, Miyazaki, Teruo, Hirayama, Takeshi, Numazawa, Mitsuteru, Matsuzaki, Yasushi
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2009
主題:
Methods
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739749/
https://ncbi.nlm.nih.gov/pubmed/19403942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D800054-JLR200
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