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Type I IL-4 Receptors Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages

Although interleukin (IL)-4 and IL-13 participate in allergic inflammation and share a receptor subunit (IL-4Rα), differential functions for these cytokines have been reported. Therefore, we compared cells expressing type I and II IL-4 receptors with cells expressing only type II receptors for their...

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Detalhes bibliográficos
Main Authors: Heller, Nicola M., Qi, Xiulan, Junttila, Ilkka S., Shirey, Kari Ann, Vogel, Stefanie N., Paul, William E., Keegan, Achsah D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739727/
https://ncbi.nlm.nih.gov/pubmed/19109239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1164795
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