Pathogenesis of Coxsackievirus-B5 acquired from intra-renal porcine islet cell xenografts in diabetic mice

BACKGROUND: We previously demonstrated the ability of a human isolate of Coxsackievirus B5 (CVB5) to productively infect adult porcine islet cells (PICs) in vitro. PICs infected with CVB5 remain viable, and upon transplantation reversed diabetes in C56BL/6 mice for up to 5 days. METHODS: In the pres...

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Bibliographic Details
Main Authors:	Myers, Suzanne E, LaRue, Rebecca, Njenga, Moses K, Shaw, Daniel P, Love, Brenda C
Format:	Artigo
Language:	Inglês
Published:	2009
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2739615/ https://ncbi.nlm.nih.gov/pubmed/19392724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-3089.2009.00522.x
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Pathogenesis of Coxsackievirus-B5 acquired from intra-renal porcine islet cell xenografts in diabetic mice

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