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Pathogenesis of Coxsackievirus-B5 acquired from intra-renal porcine islet cell xenografts in diabetic mice
BACKGROUND: We previously demonstrated the ability of a human isolate of Coxsackievirus B5 (CVB5) to productively infect adult porcine islet cells (PICs) in vitro. PICs infected with CVB5 remain viable, and upon transplantation reversed diabetes in C56BL/6 mice for up to 5 days. METHODS: In the pres...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739615/ https://ncbi.nlm.nih.gov/pubmed/19392724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-3089.2009.00522.x |
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