A Wild-Type Porcine Encephalomyocarditis Virus Containing a Short Poly(C) Tract Is Pathogenic to Mice, Pigs, and Cynomolgus Macaques

Previous studies using wild-type Encephalomyocarditis virus (EMCV) and Mengo virus, which have long poly(C) tracts (61 to 146 C's) at the 5′ nontranslated region of the genome, and variants of these viruses genetically engineered to truncate or substitute the poly(C) tracts have produced confli...

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Detalhes bibliográficos
Main Authors: LaRue, Rebecca, Myers, Suzanne, Brewer, Laurie, Shaw, Daniel P., Brown, Corrie, Seal, Bruce S., Njenga, M. Kariuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187386/
https://ncbi.nlm.nih.gov/pubmed/12915530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9136-9146.2003
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