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The Formation and Biological Significance of N7-Guanine Adducts

DNA alkylation or adduct formation occurs at nucleophilic sites in DNA, mainly the N7-position of guanine. Ever since identification of the first N7-guanine adduct, several hundred studies on DNA adducts have been reported. Major issues addressed include the relationships between N7-guanine adducts...

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Detalhes bibliográficos
Main Authors: Boysen, Gunnar, Pachkowski, Brian F., Nakamura, Jun, Swenberg, James A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739241/
https://ncbi.nlm.nih.gov/pubmed/19465146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2009.05.006
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