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Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) Tat protein is a major viral transactivator required for HIV-1 replication. In the nucleus Tat greatly stimulates the synthesis of full-length transcripts from the HIV-1 promoter by causing efficient transcriptional elongation. Tat induces...

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Autors principals: Charnay, Nicolas, Ivanyi-Nagy, Roland, Soto-Rifo, Ricardo, Ohlmann, Théophile, López-Lastra, Marcelo, Darlix, Jean-Luc
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739156/
https://ncbi.nlm.nih.gov/pubmed/19671151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-74
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