SBDS Expression and Localization at the Mitotic Spindle in Human Myeloid Progenitors

BACKGROUND: Shwachman-Diamond Syndrome (SDS) is a hereditary disease caused by mutations in the SBDS gene. SDS is clinically characterized by pancreatic insufficiency, skeletal abnormalities and bone marrow dysfunction. The hematologic abnormalities include neutropenia, neutrophil chemotaxis defects...

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Bibliografiske detaljer
Main Authors: Orelio, Claudia, Verkuijlen, Paul, Geissler, Judy, van den Berg, Timo K., Kuijpers, Taco W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738965/
https://ncbi.nlm.nih.gov/pubmed/19759903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007084
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