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SBDS Expression and Localization at the Mitotic Spindle in Human Myeloid Progenitors

BACKGROUND: Shwachman-Diamond Syndrome (SDS) is a hereditary disease caused by mutations in the SBDS gene. SDS is clinically characterized by pancreatic insufficiency, skeletal abnormalities and bone marrow dysfunction. The hematologic abnormalities include neutropenia, neutrophil chemotaxis defects...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Orelio, Claudia, Verkuijlen, Paul, Geissler, Judy, van den Berg, Timo K., Kuijpers, Taco W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738965/
https://ncbi.nlm.nih.gov/pubmed/19759903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007084
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