CXCR3 Antagonism Impairs the Development of Donor-reactive, IFN-γ-producing Effectors and Prolongs Allograft Survival

BACKGROUND: Current immunosuppression regimens are highly toxic to transplant recipients and, in many cases, acute rejection episodes occur due to escape of donor-reactive lymphocytes from the immunosuppression. T cells are the mediators of acute, cell-mediated graft damage and are hypothesized to u...

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Detaylı Bibliyografya
Asıl Yazarlar: Rosenblum, J.M., Zhang, Q-W., Siu, G., Collins, T. L., Sullivan, T., Dairaghi, D.J., Medina, J.C., Fairchild, R.L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738925/
https://ncbi.nlm.nih.gov/pubmed/19202440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31819574e9
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