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CXCR3 Antagonism Impairs the Development of Donor-reactive, IFN-γ-producing Effectors and Prolongs Allograft Survival

BACKGROUND: Current immunosuppression regimens are highly toxic to transplant recipients and, in many cases, acute rejection episodes occur due to escape of donor-reactive lymphocytes from the immunosuppression. T cells are the mediators of acute, cell-mediated graft damage and are hypothesized to u...

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Bibliografiska uppgifter
Huvudupphovsmän:	Rosenblum, J.M., Zhang, Q-W., Siu, G., Collins, T. L., Sullivan, T., Dairaghi, D.J., Medina, J.C., Fairchild, R.L.
Materialtyp:	Artigo
Språk:	Inglês
Publicerad:	2009
Ämnen:	Article
Länkar:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2738925/ https://ncbi.nlm.nih.gov/pubmed/19202440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31819574e9
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CXCR3 Antagonism Impairs the Development of Donor-reactive, IFN-γ-producing Effectors and Prolongs Allograft Survival

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