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The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
Myostatin is a member of the transforming growth factor-β (TGF-β) family and a strong negative regulator of muscle growth. Here, we present the crystal structure of myostatin in complex with the antagonist follistatin 288 (Fst288). We find that the prehelix region of myostatin very closely resembles...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738701/ https://ncbi.nlm.nih.gov/pubmed/19644449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.205 |
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