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A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy

The natural compound deguelin has promising preventive and therapeutic activity against diverse cancers by directly binding to heat-shock protein 90 (Hsp90) and thus suppressing its function. Potential side effects of deguelin over a certain dose, however, could be a substantial obstacle to its clin...

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Autori principali: Kim, Woo-Young, Chang, Dong Jo, Hennessy, Bryan, Kang, Hae-Jin, Yoo, Jakyung, Han, Seung-Ho, Kim, Yoo-Shin, Park, Hyun-Ju, Geo, Seung-Yong, Mills, Gordon, Kim, Kyu-Won, Hong, Waun Ki, Suh, Young-Ger, Lee, Ho-Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738643/
https://ncbi.nlm.nih.gov/pubmed/19139008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0184
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