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Ssa1 overexpression and [PIN(+)] variants cure [PSI(+)] by dilution of aggregates
Several cellular chaperones have been shown to affect the propagation of the yeast prions [PSI(+)], [PIN(+)] and [URE3]. Ssa1 and Ssa2 are Hsp70 family chaperones, that generally cause pro-[PSI(+)] effects since dominant negative mutants of Ssa1 or Ssa2 cure [PSI(+)], and overexpression of Ssa1 enha...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738641/ https://ncbi.nlm.nih.gov/pubmed/19422835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.063 |
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