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Functional RET G691S Polymorphism in Cutaneous Malignant Melanoma
RET proto-oncogene encodes a receptor tyrosine kinase whose ligand is glial cell line-derived neurotrophic factor (GDNF), and its polymorphism at G691S juxtamembrane region (RETp) is a germline polymorphism. Cutaneous melanomas, particularly the desmoplastic subtype, are highly neurotropic; thus we...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738597/ https://ncbi.nlm.nih.gov/pubmed/19561646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.164 |
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