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FOXO3a Promotes Tumor Cell Invasion through the Induction of Matrix Metalloproteinases
The role of the Forkhead transcription factor FOXO3a in processes that promote tumor metastasis is poorly defined. Here, we show that depletion of FOXO3a from cancer cells leads to decreased tumor size specifically due to attenuated invasive migration. During tumor progression, an increase in tumor...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738298/ https://ncbi.nlm.nih.gov/pubmed/19564415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00077-09 |
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