A Novel Gene Essential for the Development of Single Positive Thymocytes

A critical step during intrathymic T-cell development is the transition of CD4(+) CD8(+) double-positive (DP) cells to the major histocompatibility complex class I (MHC-I)-restricted CD4(−) CD8(+) and MHC-II-restricted CD4(+) CD8(−) single-positive (SP) cell stage. Here, we identify a novel gene tha...

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Autors principals: Kakugawa , Kiyokazu, Yasuda, Takuwa, Miura, Ikuo, Kobayashi, Ayako, Fukiage, Hitomi, Satoh, Rumi, Matsuda, Masashi, Koseki, Haruhiko, Wakana, Shigeharu, Kawamoto, Hiroshi, Yoshida, Hisahiro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738282/
https://ncbi.nlm.nih.gov/pubmed/19620281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00793-09
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